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But what exactly is HGH? A protein-like substance, it is produced by the pituitary gland in the base of the brain. It plays a crucial role in many of the body’s metabolic processes – too little in childhood leads to stunted growth, and too little in an adult results in excess body fat, lack of lean muscle tissue, brittle bones and thin, wrinkle-prone skin.

It has long been known that production of the hormone slows down as we grow older. By the age of 60, we make half as much HGH as we did at 20. The pharmaceutical industry originally obtained it by extracting it from the brains of dead humans (a risky process that meant some batches were contaminated with CJD, the human form of “mad cow” disease), but in 1985 it was produced synthetically. Then, in 1990, a landmark clinical trial supported its antiageing effects. Dr Daniel Rudman’s study, published in the New England Journal of Medicine, showed that HGH reversed many of the biggest markers of ageing – increasing skin thickness, reducing wrinkles and body fat, and increasing muscle mass by the equivalent of 10 to 20 years, in men in their sixties and seventies.

Subsequent studies suggested HGH also boosts libido, improves mental wellbeing, increases energy levels and metabolic rate. “Nearly 20,000 clinical studies conducted around the world document the broad benefits of pharmacological HGH therapy,” says Dr Ronald Klatz of the American Academy of AntiAgeing Medicine. “With HGH, the so-called signs of ageing can be reversed.”

The supplement has become extremely popular, even though many countries (including the UK and the States) have not approved it for anti-ageing treatment because there have been no long-term studies of its side effects in healthy users. Consequently, a black-market industry has since sprung up. Nowadays, about a third of HGH prescriptions in America are ultimately for anti-ageing purposes, according to a 2005 study published in the Journal of the American Medicine Association.

“I have about 250 patients currently on HGH,” says Dr Thierry Hertoghe, a GP with an interest in endocrinology. “I’ve been taking it myself for 13 years, and it has completely changed my life. I’m now 50, but I have no wrinkles. I need two hours less sleep than I did when I was younger, and I’ve got a much more efficient memory. My body fat is 13%. Basically, HGH stops the body cells from atrophying. I believe 70% of ageing is due to lack of growth hormone.”

The anti-ageing guru Dr Cecilia Tregear of the Wimpole Skin Care Centre in London is another doctor who has taken it herself.

“The effect was amazing,” she says. “I had so much energy, and I felt as if I was on a high all the time. I took it for three years as an experiment into its safety and had no side effects from taking a low dose.”