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Sildenafil

How does it work?

Kamagra tablets contain the active ingredient sildenafil, which is a medicine used in the treatment of erectile dysfunction (impotence). Sildenafil is called a phosphodiesterase type 5 inhibitor, and works by preventing the action of a chemical in the body called phosphodiesterase type 5.

An erection is produced via a complex chain of events, involving signals from the nervous system and the release of chemical messengers within the tissues of the penis. One of these chemical messengers is called cyclic GMP.

Cyclic GMP causes the blood vessels in the penis to widen by relaxing a thin layer of muscle found in the blood vessel walls. This allows more blood to enter the penis, which ultimately results in the penis becoming rigid and erect.

Cyclic GMP is normally broken down by another chemical in the body called phosphodiesterase type 5. Sildenafil works by preventing the action of phosphodiesterase type 5, thus stopping the breakdown of cyclic GMP. This means that the blood vessels are kept dilated for longer, improving blood flow to the penis and maintaining an erection.

As sildenafil enhances the actions of the chemical messengers responsible for producing an erection, it will only work once these messengers are present. This means that sexual stimulation is required for it to produce and maintain an erection. The dose should be taken approximately one hour before intended intercourse.

What is it used for?

  • Impotence (Erectile Dysfunction)

Warning!

  • This medicine should be taken on an empty stomach, as if it is taken with food it may take longer to work and be less effective.

  • This medicine may cause dizziness and visual disturbances. You should make sure you are aware of your reactions to this medicine before driving or operating machinery.

  • If you do feel dizzy or lightheaded after taking this medicine you should lie down until the symptoms pass.

  • If sildenafil is taken with grapefruit juice, this may cause a modest increase in the blood level of sildenafil and may increase the chance of experiencing side effects.

  • If your erection lasts longer than 4 hours (priapism), consult a doctor immediately. Treatment of this condition should not be delayed more than 6 hours, as this can cause damage to the erectile tissue in the penis and irreversible erectile dysfunction.

  • This medicine should not be taken more than once a day.